Project A1: Intrinsic and modulated dynamics in complex brain networks
Prof. Dr. Claus Hilgetag
Dept. of Computational Neuroscience, UKE
The goal of this theoretical project is to understand the dynamics of complex, large-scale brain networks on the basis of their structural topology. To that end, we advance a combined approach of connectivity databasing, graph-theoretical analyses of neural connectivity and computational modeling of neural network dynamics. In particular, we investigate brain dynamics that are altered by lesions, focal stimulation, or other kinds of neural modulation. Modeling is carried out for large-scale generic neural networks, the animal model of the ferret brain, as well as extensive connectivity data available in the SFB for the healthy and impaired human brain.