Project B7: Emergence and plasticity of architectures underlying multi-site communication
Dr. Fabio Morellini
Behavioral Biology Unit, ZMNH, UKE
Prof. Dr. Thomas Oertner
Dept. of Synaptic Physiology, ZMNH, UKE
We will use optogenetic intervention during formation and recall of spatial memories to investigate the generation of cognitive maps and the overlap between engrams of specific spatial positions. Using activity-dependent expression of light-gated chloride channels, we will determine how multiple positions in a single environment are encoded. We will investigate how entorhinal cortex, dentate gyrus and CA1 interact when spatial memories are retrieved, updated during spatial reversal learning, and consolidated during sleep.